Engineer, Synthetics/Small Molecule Processes (JP13329)
Company: 3 Key Consulting
Location: Cambridge
Posted on: April 1, 2026
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Job Description:
Job Title: Engineer, Synthetics/Small Molecule Processes
(JP13329) Location: Cambridge, MA. 02138 Business Unit: DTS
Synthetics Employment Type: Contract Duration: 2 years with likely
extensions and/or conversion to a permanent position. Rate : $38 -
$42/hour W2 Posting Date: 10/29/2024. Notes: Only qualified
candidates need apply. This is a 100% onsite position. Local
candidates to Cambridge, MA only 3 Key Consulting is hiring! We are
recruiting an Engineer for a consulting engagement with our direct
client, a leading global biotechnology company. Job Description: We
are looking for a proactive individual contributor who excels in
teamwork, problem-solving and critical thinking. Candidate must
have experience in synthetics/small molecule processes. We would
like experience working in a kilo lab or small molecule
manufacturing (preferable, but not a must have, this can be trained
once the EW is in the role). In this role, you will be responsible
for supporting the process development and technical transfer of
client’s synthetic drug substance processes by first demonstrating
scale-up execution in the kilo lab. This role also requires acting
as an equipment and instrument owner, and leading inventory
maintenance and chemical/equipment ordering and shipping. The
Scale-up Lab (SUL) is integral to the optimization, scale-up, and
technology transfer of client’s drug substance intermediates and
final API. This enabling capability within the DSTS organization
critically supports programs across all stages of development,
including route selection, process optimization, and process
characterization. Top Must Have Skill Sets: Experience working in a
chemical synthesis lab Individual contributor, able to perform
tasks with minimal to no supervision Good communication skills
Synthetics/small molecule processes This role also requires acting
as an equipment and instrument owner, and leading inventory
maintenance and chemical/equipment ordering and shipping. Day to
Day Responsibilities: Lead operations in the Scale-Up Lab (SUL):
Act as a superuser of all SUL equipment and accessories. Provide
on-the-floor support to ensure successful scale up and rapid
problem solving and decision making. Enable safe execution of SUL
operations with minimal to no supervision. Work closely with
process development chemists and engineers to generate and
interpret data, providing improved understanding and guidance for
synthetic (small molecule) drug substances. Executions of
bench/kilo laboratory experimentation and process
modeling/simulation to design and optimize robust synthetic
processes. Provide hands-on troubleshooting support related to
processing and process equipment problems Represent the
organization within a multi-functional team to ensure deliverables
are aligned with the timeline, ensuring key achievements are
established and met. Apply standard engineering techniques and
procedures to provide solutions to a variety of technical chemical
and process issues that will be encountered during process
development, tech transfer and scale-up Author, review, and/or
approve process documentation, master batch records, operational
SOPs, and safety protocols needed to support SUL. Order and
maintian non-GMP chemical storage within SUL Update compound and
material inventory for projects to demonstrate in AMA SUL in
coordination with step lead Documentation of Real-Time Execution
and Verification of Processing Steps in the Batch Sheet
Instructions Equipment upkeep and maintenance: Coordinate equipment
scheduling for new experiment requests. Submit work orders,
independently manage equipment maintenance, and support equipment
troubleshooting. Support preventative maintenance operations
related to lab equipment and utilities, including, but not limited
to, reactors, filters, rupture discs, heat transfer unit and
chiller equipment. Lead lab inventory management, including
monitoring usage, ordering, and restocking of consumables.
Establish a management system for equipment replacement parts and
maintain stock. Demonstrate expertise with lab equipment handling
and repair to troubleshoot challenges. Execute Installation
Operational Verification (IOV) and Evaluate Performance and
Reliability of New Equipment Lab improvements and knowledge
management: Support efforts for lab upgrades and optimization.
Assist in authoring training documentation for lab operations and
equipment. Monitor training compliance and coordinate training
refreshers through the client’s training system. Participate in and
curate content for core and steering team meetings. Participate in
EHSS risk assessments and periodic reviews, acting as an SME.
Coordinate mitigations resulting from RAs and reviews. Provide
hands-on training and oversight for new users and refresher
training for previous users. Basic Qualifications: Bachelor’s in
chemistry or chemical engineering with at least two years of
experience (can be academic or professional in the synthetics/small
molecule processes). High school diploma / GED and 8 years of
related Engineering or Operations experience Associate’s degree and
4 years of related Engineering or Operations experience Bachelor’s
or Master’s degree and 2 years of relatedEngineering or Operations
experience Preferred Qualifications: Experience working in a kilo
lab or small molecule manufacturing (preferable, but not a must
have, this can be trained once the EW is in the role). Interview
Process: 2 Rounds; phone screen followed by final round either
virtual or an onsite interview in Cambridge Office We invite
qualified candidates to send your resume to
resumes@3keyconsulting.com . If you decide that you’re not
interested in pursuing this particular position, please feel free
to take a look at the other positions on our website
www.3keyconsulting.com/careers. You are also welcome to share this
opportunity with anyone you think might be interested in applying
for this role. Regards, 3KC Talent Acquisition Team
Keywords: 3 Key Consulting, Lowell , Engineer, Synthetics/Small Molecule Processes (JP13329), Engineering , Cambridge, Massachusetts
